Rb(Phospho Thr821) Polyclonal Antibody, 100ul Adenovirus Packaging Naturally occurring read-through transcription exists

Naturally occurring read-through transcription exists between this gene and the neighboring upstream malonyl-CoA decarboxylase (MLYCD) gene| but the read-through transcripts are unlikely to produce a protein product

This gene encodes an orphan nuclear receptor which is a member of the nuclear hormone receptor family

The encoded protein (SWI/SNF related

Associates with the 9-1-1 complex

neurophysin 2 and copeptin

Rb(Phospho Thr821) Polyclonal Antibody, 100ul Adenovirus Packaging Naturally occurring read-through transcription existsThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.