SIM1 Rabbit Polyclonal Antibody, 100ul Centrifugal Filter This gene is co-transcribed with

This gene is co-transcribed with the U69 small nucleolar RNA gene

Alternative splicing results in multiple tr

GO annotations related to this gene include identical protein binding and GTPase activity

Upon phosphorylation

The encoded protein localizes to centrosomes and microtubules| and associates with the GTP-activated forms of Ras| Rap1| and several other Ras-like small GTPases

SIM1 Rabbit Polyclonal Antibody, 100ul Centrifugal Filter This gene is co-transcribed withSIM1 and SIM2 genes are Drosophila single minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull