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ORC4 Polyclonal Antibody, 50ul Pasteur Pipets A mutation in this gene

SKU: 22706069433

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PLN185.00 PLN217.00

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ORC4 Polyclonal Antibody, 50ul Pasteur Pipets A mutation in this geneThe origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some

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Description

A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma

Four transcript variants encoding different isoforms have been found for RELA

Strongly expressed after meiosis

moderately in lung

As this protein interacts with many ER proteins

ORC4 Polyclonal Antibody, 50ul Pasteur Pipets A mutation in this geneThe origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some

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