Rat E3 Ubiquitin-protein Ligase Trim63, TRIM63 ELISA Kit, 96T Mammalian Expression which is located on the

which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration

ANO2 belongs to a family of calcium-activated chloride channels (CaCCs) (reviewed by Hartzell et al

Silencing events often occur within introns of transcriptionally active genes

tissue specificity:Ubiquitously expressed with higher expression found in heart and placenta

The gene product interacts with certain inflammatory response factors| and polymorphisms of this gene may be involved in the pathogenesis of Alzheimer's disease

Rat E3 Ubiquitin-protein Ligase Trim63, TRIM63 ELISA Kit, 96T Mammalian Expression which is located on theE3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I TNNI3 and probably of other sarcomeric