ND1 Polyclonal Antibody, 50ul Site-directed Mutagenesis Mutations in TSC1 have been

Mutations in TSC1 have been associated with tuberous sclerosis

Dimerization with alphaE permits binding to the ligand epithelial cadherin

Up-regulated upon mitogenic stimulation

The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus

which in turn activates a host of inflammatory-related target genes

ND1 Polyclonal Antibody, 50ul Site-directed Mutagenesis Mutations in TSC1 have beenMT ND1 is a Protein Coding gene. Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Diseases associated with MT ND1 include melas syndrome and leber hereditary optic neuropathy.