FAT10 Polyclonal Antibody, 100ul General Lab Use CENPP is a subunit of

CENPP is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al

a programmed cell death process

which may be important for neoplastic transformation and tumor progression

is amplified in the mouse transformed 3T3 cell line

ZFP36L2 is a member of the TIS11 family of early response genes

FAT10 Polyclonal Antibody, 100ul General Lab Use CENPP is a subunit ofFAT10, also designated Ubiquitin D or Diubiquitin, is a 165 amino acid protein encoded in the major histocompatibility complex (MHC) that consists of two domains which share significant homology with ubiquitin. Each domain contains two cysteines, along with a free C terminal diglycine motif required for FAT10 conjugate formation. FAT10 is inducible by interferon g and tumor necrosis factor a (TNF). The FAT10 protein interacts with MAD2, a component of