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GLIS3 Rabbit Polyclonal Antibody, 20ul Antibody Humanization SRRM1 and TRA2B/SFRS10

SKU: 24689241620

4.6
EUR111.00 EUR160.00

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GLIS3 Rabbit Polyclonal Antibody, 20ul Antibody Humanization SRRM1 and TRA2B/SFRS10This gene is a member of the GLI similar zinc finger protein family and encodes a nuclear protein with five C2H2 type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells the thyroid eye liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants

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Description

SRRM1 and TRA2B/SFRS10

The proteins encoded by this gene and another testis-specific transcription factor| SOHLH1| can form heterodimers| in addition to homodimers

A similar protein in mouse binds E12| a transcriptional regulator of immunoglobulin genes

|tissue specificity:Expressed in thymus| T-cells| NK cells| mast cells and| at lower levels| in spleen

and probably also in transcription regulation

GLIS3 Rabbit Polyclonal Antibody, 20ul Antibody Humanization SRRM1 and TRA2B/SFRS10This gene is a member of the GLI similar zinc finger protein family and encodes a nuclear protein with five C2H2 type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells the thyroid eye liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants

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