TSP50 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos In nonmuscle cells| the cytoskeletal

In nonmuscle cells| the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions| where it is involved in binding actin to the membrane

Two pseudogenes of this gene are located on the long arm of chromosome 17

through binding to its C-terminal region

endothelial cell growth and migration

Aberrant expression of this gene may paly a role in tumorigenesis

TSP50 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos In nonmuscle cells| the cytoskeletalAlthough related to peptidase S1 family, lacks the conserved active Ser residue in position 310 which is replaced by a Thr, suggesting that it has no protease activity.,miscellaneous: DNA hypomethylation is accompanied by the expression of the gene in the testis.,Belongs to the peptidase S1 family.,Contains 1 peptidase S1 domain.,tissue specificity: Testis specific. Differentially expressed in some breast cancer tissues.,