EGF Receptor(Phospho-Tyr1068) Rabbit Polyclonal Antibody, 50ul Erlenmeyer Flasks Mutations in NBN are associated

Mutations in NBN are associated with Nijmegen breakage syndrome

CCR4 and CCR5

and is phosphorylated in response to cytokine stimulation

This gene is intronless and the encoded protein is secreted

Four transcript variants encoding two different isoforms have bee

EGF Receptor(Phospho-Tyr1068) Rabbit Polyclonal Antibody, 50ul Erlenmeyer Flasks Mutations in NBN are associatedThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.