Mouse Protein Wnt-4, WNT4ELISA Kit , 96T Plates & Dishes which is a coactivator for

which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al

Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities

Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture

which is evolutionarily conserved

The encoded protein has an N-terminal forkhead-associated domain

Mouse Protein Wnt-4, WNT4ELISA Kit , 96T Plates & Dishes which is a coactivator forLigand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in the embryonic development of the urogenital tract and the lung (PubMed: 7990960, PubMed: 9989404, PubMed: 16054034, PubMed: 17537789, PubMed: 19830824, PubMed: 26321050). Required for normal mesenchyme to epithelium transition during embryonic kidney development (PubMed: 7990960, PubMed: 16054034, PubMed: 17537789, PubMed: 19830824).