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SSRP1 Rabbit Polyclonal Antibody, 20ul Organelle Studies Alternate transcriptional splice variants of

SKU: 25958926353

4.0
PLN97.20 PLN133.20

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SSRP1 Rabbit Polyclonal Antibody, 20ul Organelle Studies Alternate transcriptional splice variants ofThe protein encoded by this gene is a subunit of a heterodimer that along with SUPT16H forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition

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Description

Alternate transcriptional splice variants of STK11 have been observed but have not been thoroughly characterized

Excellent mixing (200-1500rpm)

Transcripts from this gene lack polyA tails| instead

The protein encoded by this gene is part of the Mediator complex| which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes

This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A

SSRP1 Rabbit Polyclonal Antibody, 20ul Organelle Studies Alternate transcriptional splice variants ofThe protein encoded by this gene is a subunit of a heterodimer that along with SUPT16H forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition

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