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CLP1 Polyclonal Antibody, 20ul Antibodies Although the BCR-ABL fusion protein

SKU: 26006256928

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CLP1 Polyclonal Antibody, 20ul Antibodies Although the BCR-ABL fusion proteinThis gene encodes a member of the Clp1 family. The encoded protein is a multifunctional kinase which is a component of the tRNA splicing endonuclease complex and a component of the pre mRNA cleavage complex II. This protein is implicated in tRNA, mRNA, and siRNA maturation. Mutations in this gene are associated with pontocerebellar hypoplasia type 10 (PCH10). Alternatively splice transcript variants encoding different isoforms have been found for this

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Description

Although the BCR-ABL fusion protein has been extensively studied

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The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins

Rap-Hodgkin syndrome (RHS)

Alternative splicing of this gene results in two transcript variants encoding distinct isoforms

CLP1 Polyclonal Antibody, 20ul Antibodies Although the BCR-ABL fusion proteinThis gene encodes a member of the Clp1 family. The encoded protein is a multifunctional kinase which is a component of the tRNA splicing endonuclease complex and a component of the pre mRNA cleavage complex II. This protein is implicated in tRNA, mRNA, and siRNA maturation. Mutations in this gene are associated with pontocerebellar hypoplasia type 10 (PCH10). Alternatively splice transcript variants encoding different isoforms have been found for this

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