IκB alpha(Phospho-Ser32) Rabbit Polyclonal Antibody, 100ul Vacuum Filter Mitogen-activated protein kinase 10 encoded

Mitogen-activated protein kinase 10 encoded by MAPK10 is a member of the MAP kinase family

Multiple phosphorylation sites have been identified: ser297 and Ser392 mediate 14-3-3 binding

also known as AGBL2 (ATP/GTP binding protein-like 2)

An important paralog of this gene is P2RY14

and cell migration

IκB alpha(Phospho-Ser32) Rabbit Polyclonal Antibody, 100ul Vacuum Filter Mitogen-activated protein kinase 10 encodedThis gene encodes a member of the NF kappa B inhibitor family which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell