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Duffy Polyclonal Antibody, 50ul In vitro Assessment The encoded protein is stimulated

SKU: 26577875157

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Duffy Polyclonal Antibody, 50ul In vitro Assessment The encoded protein is stimulatedThe atypical chemokine receptor 1 (Duffy blood group) encoded by ACKR1 is a glycosylated membrane protein and a non specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene.

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Description

The encoded protein is stimulated by transforming growth factor beta

Mutations in this gene have been associated with Oguchi disease

The alpha and beta tubulins represent the major components of microtubules| while gamma tubulin plays a critical role in the nucleation of microtubule assembly

It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates

The MED12 protein is essential for activating CDK8 kinase

Duffy Polyclonal Antibody, 50ul In vitro Assessment The encoded protein is stimulatedThe atypical chemokine receptor 1 (Duffy blood group) encoded by ACKR1 is a glycosylated membrane protein and a non specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene.

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