CKR-5 Polyclonal Antibody, 20ul[BT-AP07729] Nucleic Acid Isolation & Purification Defects in TMEM237 are a

Defects in TMEM237 are a cause of Joubert syndrome-14

Metallocarboxypeptidase that mediates deglutamylation of target proteins

embryogenesis

resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network

morphologic development

CKR-5 Polyclonal Antibody, 20ul[BT-AP07729] Nucleic Acid Isolation & Purification Defects in TMEM237 are aThis gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co receptor for macrophage tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include