RFWD3 Polyclonal Antibody, 100ul DNA Fragments Belongs to the DNA polymerase
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RFWD3 Polyclonal Antibody, 100ul DNA Fragments Belongs to the DNA polymeraseRFWD3, also named as RNF201, is a E3 ubiquitin protein ligase that mediates the ubiquitination of p53 TP53 in the late response to DNA damage, and acts as a positive regulator of p53 TP53 stability, thereby regulating the G1 S DNA damage checkpoint. RFWD3 may act by catalyzing the formation of short polyubiquitin chains on p53 TP53 that are not targeted to the proteasome. In response to ionizing radiation, It interacts with MDM2 and enhances p53 TP53
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