Calpain 2 Polyclonal Antibody, 50ul Roller Bottles Mutations in Nkx2-6 are associated

Mutations in Nkx2-6 are associated with persistent truncus arteriosus

and serves as a scaffold protein in signal transduction

leads to steeper calcium sensitivity

The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene

This protein also plays an important role in HDL metabolism and cholesterol homeostasis

Calpain 2 Polyclonal Antibody, 50ul Roller Bottles Mutations in Nkx2-6 are associatedThe calpains, calcium activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach specific, and muscle specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. CAPN2 (calpain 2) encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional