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SRGP2 Rabbit Polyclonal Antibody, 100ul Bio-Reaction Tube The protein encoded by this

SKU: 27117287010

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SRGP2 Rabbit Polyclonal Antibody, 100ul Bio-Reaction Tube The protein encoded by thisThis locus encodes a member of the SLIT ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1 and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species the paralogs are found only in the genus Homo and not in the genomes of non human great apes. Alternatively spliced

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Description

The protein encoded by this gene is a member of the tripartite motif (TRIM) family

The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes

and from NG108 and PC-12 cells

disease:Defects in BMP4 are the cause of microphthalmia syndromic type 6 (MCOPS6)

COL14A1 (collagen type XIV alpha 1 chain) encodes the alpha chain of type XIV collagen

SRGP2 Rabbit Polyclonal Antibody, 100ul Bio-Reaction Tube The protein encoded by thisThis locus encodes a member of the SLIT ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1 and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species the paralogs are found only in the genus Homo and not in the genomes of non human great apes. Alternatively spliced

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