Rb Polyclonal Antibody, 20ul[BT-AP07689] DNA Libraries Synthesis High expression of the encoded

High expression of the encoded protein may be associated with elevated heart left ventricular mass

a disorder characterized by recurrent episodes of fever associated with lymphadenopathy

as well as some non-protein coding variants

and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria

It has in vitro and in vivo binding activity with CBP and p300

Rb Polyclonal Antibody, 20ul[BT-AP07689] DNA Libraries Synthesis High expression of the encodedRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.