Paxillin Polyclonal Antibody, 50ul[BT-AP06956] PCR Series An important paralog of this

An important paralog of this gene is IGHG4

Pseudogenes related to this gene are located on chromosomes 1

This gene is located on human chromosome 11q24| a region frequently altered in cancers

similar to Vps4 protein in yeast

gene silencing

Paxillin Polyclonal Antibody, 50ul[BT-AP06956] PCR Series An important paralog of thisPXN encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for PXN. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.