Acetyl Kine Polyclonal Antibody, 100ul Long RNA Synthesis alternative products:Additional isoforms seem to

alternative products:Additional isoforms seem to exist|Catalytic activity:Cleaves aggrecan at the 360-Ser-|-Phe-361 site

one on chromosome 15 and the other on chromosome 21

Alternate splicing of this gene generates several transcript variants encoding different isoforms

2002 [PubMed 12191433])

Mutations in this gene also cause autosomal recessive retinitis pigmentosa

Acetyl Kine Polyclonal Antibody, 100ul Long RNA Synthesis alternative products:Additional isoforms seem toAcetylation of lysine like phosphorylation of serine threonine or tyrosine is an important reversible modification controlling protein activity. The conserved amino terminal domains of the four core histones (H2A H2B H3 and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs) . Signaling resulting in acetylation deacetylation of histones transcription factors and other proteins