Neu Polyclonal Antibody, 20ul[BT-AP05904] Protein Expression Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene

which results in a fusion gene that is present in the majority of Ewing sarcoma cases

Over-expressed in breast cancer

ART1 (ADP-ribosyltransferase 1) was previously designated ART2

Two transcript variants encoding different isoforms have been found for MRPL22

Neu Polyclonal Antibody, 20ul[BT-AP05904] Protein Expression Multiple alternatively spliced transcript variantsERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Receptor tyrosine protein kinase erbB 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those