Human Acid Sphingomyelinase-like Phosphodiesterase 3B, SMPDL3B ELISA Kit , 96T Bottle-Top Dispenser Binding of the SH2 domains

Binding of the SH2 domains of PI3K to phosphotyrosines on IRS1 leads to the activation of PI3K and the generation of phosphatidylinositol-(3

Expression of ITGA3 may be correlated with breast cancer metastasis

some of which do not encode a protein with a predicted signal peptide

enteropathy

This gene encodes a member of the testis-specific protein Y-encoded

Human Acid Sphingomyelinase-like Phosphodiesterase 3B, SMPDL3B ELISA Kit , 96T Bottle-Top Dispenser Binding of the SH2 domainsLipid modulating phosphodiesterase (PubMed: 26095358). Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll like receptor signaling (By similarity). Has in vitro phosphodiesterase activity, but the physiological substrate is unknown (PubMed: 26095358). Lacks activity with phosphocholine containing lipids, but can cleave CDP choline, and