AP1B1 Rabbit Polyclonal Antibody, 100ul Inoculating Loops/Needles Recombination-associated motifs and translin-binding sites

Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations

also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2)

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These mutations have been shown to cause diverse changes in the pattern of DNA methylation

Multiple transcript variants encoding different isoforms have been found for NR4A1

AP1B1 Rabbit Polyclonal Antibody, 100ul Inoculating Loops/Needles Recombination-associated motifs and translin-binding sitesAdaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex