Rtn-3 Monoclonal Antibody, 50ul[BT-MCA1109] Plasmid Preparation The eukaryotic translation initiation factor

The eukaryotic translation initiation factor 4 gamma 1 encoded by EIF4G1 is a component of the multi-subunit protein complex EIF4F

This subunit associates with beta 1

The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P

The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme

The encoded protein itself is found in a complex of proteins

Rtn-3 Monoclonal Antibody, 50ul[BT-MCA1109] Plasmid Preparation The eukaryotic translation initiation factorThis gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta amyloid converting enzyme 1 (BACE1), and the production of amyloid beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid beta, suggesting that reticulon proteins are negative modulators of BACE1 in