RNF149 Polyclonal Antibody, 50ul Monoclonal Antibodies Mutations in this gene are

Mutations in this gene are the cause of thrombocythemia 1

and acts as an autocrine factor to induce apoptosis in endothelial cells

The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments

NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors

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RNF149 Polyclonal Antibody, 50ul Monoclonal Antibodies Mutations in this gene areRNF149 (Ring Finger Protein 149) is a Protein Coding gene. GO annotations related to this gene include ligase activity and ubiquitin protein transferase activity. An important paralog of this gene is RNF167. 3 ubiquitin protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation.