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FAK(Phospho Tyr397) Polyclonal Antibody, 100ul RNA Synthesis This kinase contains multiple functional

SKU: 28381286349

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FAK(Phospho Tyr397) Polyclonal Antibody, 100ul RNA Synthesis This kinase contains multiple functionalThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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Description

This kinase contains multiple functional domains

PER3 is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL

The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family

Stimulates cancer-associated fibroblast (CAF) proliferation by a rapid genomic response through the EGFR/ERK transduction pathway

as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form

FAK(Phospho Tyr397) Polyclonal Antibody, 100ul RNA Synthesis This kinase contains multiple functionalThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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