U-PAR Rabbit Polyclonal Antibody, 50ul Plasma It has been verified by

It has been verified by different cell culture tests that there is almost no cell attachment on the surface and enables cell spheroid culture in a rapid

Importin-alpha binds the NLS

Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of p16(INK4a)

The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS16

The encoded protein has putative tumor suppressor function and decreased expression has been observed in tumors

U-PAR Rabbit Polyclonal Antibody, 50ul Plasma It has been verified byActs as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis independent signal transduction activation effects of U PA. It is subject to negative feedback regulation by U PA which cleaves it into an inactive form. Contains 3 UPAR Ly6 domains. subunit: Monomer (Probable). Interacts with MRC2.