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DDR1 Polyclonal Antibody, 100ul[BT-AP02536] Pipette Micro Tips Ligands for Eph receptors include

SKU: 28591225863

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DKK123.75 DKK147.75

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DDR1 Polyclonal Antibody, 100ul[BT-AP02536] Pipette Micro Tips Ligands for Eph receptors includeReceptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. Discoidin domain receptor tyrosine kinase 1 encoded by DDR1 belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen.

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Description

Ligands for Eph receptors include ephrin-A4 (LERK-4) which binds EphA3 and EphB1

Polymorphisms that increase expression of this gene have been shown to increase vascular inflammation| and an association of this gene with myocardial infarction has been demonstrated

The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas

where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction

Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine

DDR1 Polyclonal Antibody, 100ul[BT-AP02536] Pipette Micro Tips Ligands for Eph receptors includeReceptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. Discoidin domain receptor tyrosine kinase 1 encoded by DDR1 belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen.

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