Phospho-ATRIP (S224) Polyclonal Antibody, 20ul Measuring Instruments Mutations in this gene are

Mutations in this gene are associated with type 1 pachyonychia congenita

each of which contains a highly specific cleavage signal

5% of the human genome with about 81 million bases encoding over 1

They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens

membrane phospholipids

Phospho-ATRIP (S224) Polyclonal Antibody, 20ul Measuring Instruments Mutations in this gene areATRIP (ATR interacting protein) encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for ATRIP.