GRK 2(Phospho Ser29) Polyclonal Antibody, 20ul 3D Cell Culture Consumables also acts as a transcriptional

also acts as a transcriptional repressor

Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin

An important paralog of this gene is CSNK1G2

This gene is found in the small histone gene cluster on chromosome 6p22-p21

Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases

GRK 2(Phospho Ser29) Polyclonal Antibody, 20ul 3D Cell Culture Consumables also acts as a transcriptionalThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.