PUMA Polyclonal Antibody, 50ul Centrifuges Forkhead box protein B1

Forkhead box protein B1

actin dependent regulator of chromatin

May play a role in cytoskeletal stability

This proto-oncogene may play a role in the regulation of embryonic development and cell growth

and thus functions as a regulator of cytokine receptor signaling

PUMA Polyclonal Antibody, 50ul Centrifuges Forkhead box protein B1BBC3 encodes a member of the BCL 2 family of proteins. This family member belongs to the BH3 only pro apoptotic subclass. BCL2 binding component 3 cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti apoptotic Bcl 2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro apoptotic role, BBC3 is a potential drug target for cancer