GAS3 Polyclonal Antibody, 100ul Virus Packaging The ASC-1 complex is a

The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1)

Contains 6 Ig-like C2-type (immunoglobulin-like) domains

The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine

Three transcript variants encoding two different isoforms have been found for ERAP1

The protein lacks critical active site residues and thus is suggested to be proteolytically inactive

GAS3 Polyclonal Antibody, 100ul Virus Packaging The ASC-1 complex is aPMP22 (peripheral myelin protein 22) encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue specific expression. Various mutations of PMP22 are causes of Charcot Marie Tooth disease Type IA, Dejerine Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants.