p53 Polyclonal Antibody, 50ul[BT-AP06808] Antibody Development CENPQ is a subunit of

CENPQ is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al

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A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient

Multiple alternatively spliced transcript variants encoding different isoforms have been identified in CD4

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p53 Polyclonal Antibody, 50ul[BT-AP06808] Antibody Development CENPQ is a subunit ofTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.