Rat Adisintegrin and Metalloproteinase with Thrombospondin Motifs 4, ADAMTS4 ELISA Kit, 96T Protein Post-translational Modification Component of the heterotrimeric SMAD2/SMAD3-SMAD4

Component of the heterotrimeric SMAD2/SMAD3-SMAD4 complex that forms in the nucleus and is required for the TGF-mediated signaling (PubMed: 25514493)

protecting cells from oxidative stress

May also play a role in the pre-TCR activation cascade leading to the maturation of alpha/beta T-cells and may participate in the regulation of DNA accessibility in the TCR-J(alpha) locus (PubMed: 9881970

EIF4E and RENT2

This gene encodes a beta isoform of the regulatory subunit B56 subfamily

Rat Adisintegrin and Metalloproteinase with Thrombospondin Motifs 4, ADAMTS4 ELISA Kit, 96T Protein Post-translational Modification Component of the heterotrimeric SMAD2/SMAD3-SMAD4Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Cleaves aggrecan at the '392 Glu Ala 393' site.