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AKT mouse Monoclonal Antibody(10D6), 50ul Petri Dishes Since the encoded protein has

SKU: 30149302521

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AKT mouse Monoclonal Antibody(10D6), 50ul Petri Dishes Since the encoded protein hasThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

Since the encoded protein has typical features of a transcription factor| it is postulated to be a repressor of gene expression

The protein encoded by this intronless gene belongs to the highly variable methyltransferase superfamily

The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells

This gene belongs to the MAP kinase superfamily

The encoded protein may function as a transcription factor

AKT mouse Monoclonal Antibody(10D6), 50ul Petri Dishes Since the encoded protein hasThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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