Six5 Polyclonal Antibody, 20ul Recombinant Protein Expression Mutations in this gene have

Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK)

PER3 is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL

A related pseudogene has been defined on chromosome 16

An important paralog of this gene is ATG9B

The olfactory receptor gene family is the largest in the genome

Six5 Polyclonal Antibody, 20ul Recombinant Protein Expression Mutations in this gene haveSIX homeobox 5 encoded by SIX5 is a homeodomain containing transcription factor that appears to function in the regulation of organogenesis. SIX5 is located downstream of the dystrophia myotonica protein kinase gene. Mutations in this gene are a cause of branchiootorenal syndrome type 2.