UBA6 Polyclonal Antibody, 100ul Biochemical Reagents Defects in this gene are

Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D)

Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP)

Polymorphisms in this gene are associated with systemic lupus erythematosus and allergic rhinitis

the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs)

|tissue specificity:Ubiquitous

UBA6 Polyclonal Antibody, 100ul Biochemical Reagents Defects in this gene areModification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin like proteins controls many signaling networks and requires a ubiquitin activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin like proteins (Jin et al., 2007