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CD11b Polyclonal Antibody, 20ul[BT-AP14795] Recombinant Protein Expression maps to chromosome 6p21

SKU: 30411586734

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DKK97.20 DKK132.20

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CD11b Polyclonal Antibody, 20ul[BT-AP14795] Recombinant Protein Expression maps to chromosome 6p21This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte specific integrin referred to as macrophage receptor 1 ('Mac 1'), or inactivated C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to

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Description

maps to chromosome 6p21

|tissue specificity:Ubiquitous| with higher levels in heart| pancreas and testis| and lower levels in kidney and brain

SIX homeobox 5 encoded by SIX5 is a homeodomain-containing transcription factor that appears to function in the regulation of organogenesis

Alternative splicing of CDC14A results in several transcript variants encoding distinct isoforms

are integral membrane proteins containing 7 putative transmembrane domains (TMs)

CD11b Polyclonal Antibody, 20ul[BT-AP14795] Recombinant Protein Expression maps to chromosome 6p21This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte specific integrin referred to as macrophage receptor 1 ('Mac 1'), or inactivated C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to

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