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TALK-2 Polyclonal Antibody, 50ul In vitro Assessment GO annotations related to this

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TALK-2 Polyclonal Antibody, 50ul In vitro Assessment GO annotations related to thisThe protein encoded by KCNK17 (potassium two pore domain channel subfamily K member 17) belongs to the family of potassium channel proteins containing two pore forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. KCNK17 is activated at alkaline pH. Alternatively spliced transcript variants encoding different isoforms have been found for KCNK17.

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Description

GO annotations related to this gene include motor activity and cytoskeletal protein binding

The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs

and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies

This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants

Serine/threonine-protein kinase 24 is cleaved into two chains by caspases

TALK-2 Polyclonal Antibody, 50ul In vitro Assessment GO annotations related to thisThe protein encoded by KCNK17 (potassium two pore domain channel subfamily K member 17) belongs to the family of potassium channel proteins containing two pore forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. KCNK17 is activated at alkaline pH. Alternatively spliced transcript variants encoding different isoforms have been found for KCNK17.

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