PKC alpha(Phospho Tyr657) Polyclonal Antibody, 50ul Proteases The encoded protein acts as

The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG

which suggests its involvement in the regulation of transcription

Expressed in atopic dermatitis| allergic contact dermatitis skin| and psoriasis| in both the eptdermis and dermis

Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid

which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production

PKC alpha(Phospho Tyr657) Polyclonal Antibody, 50ul Proteases The encoded protein acts asProtein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile