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TRPC6 Rabbit Polyclonal Antibody, 100ul RNA Tools Mutations at GCLC have been

SKU: 31567273896

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TRPC6 Rabbit Polyclonal Antibody, 100ul RNA Tools Mutations at GCLC have beenThe protein encoded by this gene forms a receptor activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).

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Description

Mutations at GCLC have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction

while the vent cap prevents contamination

Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon

It dissociates in S phase when LIN9| LIN37| LIN52 and LIN54 form a subcomplex that binds to MYBL2

The protein encoded by this gene is a member of the STAT family of transcription factors

TRPC6 Rabbit Polyclonal Antibody, 100ul RNA Tools Mutations at GCLC have beenThe protein encoded by this gene forms a receptor activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).

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