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Rb Polyclonal Antibody, 100ul[BT-AP07692] Monoclonal Antibodies It inhibits many proteases

SKU: 31680210544

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DKK141.00 DKK180.00

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Rb Polyclonal Antibody, 100ul[BT-AP07692] Monoclonal Antibodies It inhibits many proteasesThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

It inhibits many proteases

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication

although it may play a role in mammalian hair follicle development

it is a ligand for cell surface G protein-coupled receptors

Achieve maximum stability with storage at 2-8℃

Rb Polyclonal Antibody, 100ul[BT-AP07692] Monoclonal Antibodies It inhibits many proteasesThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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