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IFN- Alpha R2 Polyclonal Antibody, 20ul Palm Micro Centrifuges Heat shock protein beta-2 encoded

SKU: 31845516922

4.8
USD97.20 USD128.20

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IFN- Alpha R2 Polyclonal Antibody, 20ul Palm Micro Centrifuges Heat shock protein beta-2 encodedInterferon alpha beta receptor 2 encoded by IFNAR2 is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene.

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Description

Heat shock protein beta-2 encoded by HSPB2 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule

strong impact resistance and high temperature resistance of up to 121°C

the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes

This protein cleaves and activates caspases 3 and 7

This protein is localized in the nucleus and contains an E1A-type zinc finger domain

IFN- Alpha R2 Polyclonal Antibody, 20ul Palm Micro Centrifuges Heat shock protein beta-2 encodedInterferon alpha beta receptor 2 encoded by IFNAR2 is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene.

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