CD45 Monoclonal Antibody, 100ul Peripheral Blood Separation Tube WRN is a DNA helicase

WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome

Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis

attention-deficit hyperactivity disorder

and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus

Its product probably functions as an adhesion molecule and/or signaling receptor

CD45 Monoclonal Antibody, 100ul Peripheral Blood Separation Tube WRN is a DNA helicaseThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been