ITGA2B Rabbit Polyclonal Antibody, 50ul[BT-AP10698] Centrifuge Tube (Bottle) Mutations in this gene cause

Mutations in this gene cause lissencephaly 4

Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow

Contains 1 C2 domain

Primary glomerulonephritis with immune deposits and age-related macular degeneration are other conditions associated with mutations of this gene

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ITGA2B Rabbit Polyclonal Antibody, 50ul[BT-AP10698] Centrifuge Tube (Bottle) Mutations in this gene causeThis gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha IIb beta 3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system by mediating platelet aggregation. Mutations in this gene are associated with platelet type bleeding