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Prothrombin Polyclonal Antibody, 100ul[BT-AP07416] Enzyme-Linked Immunosorbent Assay (ELISA) This protein transports low-density lipoproteins

SKU: 3237808340

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Prothrombin Polyclonal Antibody, 100ul[BT-AP07416] Enzyme-Linked Immunosorbent Assay (ELISA) This protein transports low-density lipoproteinsCoagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia.

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Description

This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol

Decreased expression of this gene may be associated with tumor growth and metastasis

Multiple transcript variants encoding different isoforms have been found for BCAR3

The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma

upon stress to the ER

Prothrombin Polyclonal Antibody, 100ul[BT-AP07416] Enzyme-Linked Immunosorbent Assay (ELISA) This protein transports low-density lipoproteinsCoagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia.

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