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PTEN (Acetyl Lys402) Polyclonal Antibody, 50ul Monoclonal Antibody Preparation which is thought to act

SKU: 32385685702

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PTEN (Acetyl Lys402) Polyclonal Antibody, 50ul Monoclonal Antibody Preparation which is thought to actPTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by PTEN is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases,phosphatase and tensin homolog preferentially dephosphorylates

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Description

which is thought to act as a transcription factor

This protein functions as a co-chaperone with heat shock protein 90 (HSP90)

This complex binds to the promoters of snRNA genes transcribed by either RNA polymerase II or III and recruits other regulatory factors to activate snRNA gene transcription

Each domain contains two cysteines

Gene Ontology (GO) annotations related to this gene include microtubule binding

PTEN (Acetyl Lys402) Polyclonal Antibody, 50ul Monoclonal Antibody Preparation which is thought to actPTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by PTEN is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases,phosphatase and tensin homolog preferentially dephosphorylates

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