SQSTM1/p62(Phospho-Thr269/Ser272) Rabbit Polyclonal Antibody, 100ul DNA Libraries Synthesis TOLLIP encodes a ubiquitin-binding protein

TOLLIP encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components

With 50 Units/μL of activity in just 50 μL

that is a 20S core alpha subunit

Mutations in this gene cause autosomal dominant severe congenital neutropenia

This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells| the thyroid| eye| liver and kidney

SQSTM1/p62(Phospho-Thr269/Ser272) Rabbit Polyclonal Antibody, 100ul DNA Libraries Synthesis TOLLIP encodes a ubiquitin-binding proteinThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa B (NF kB) signaling pathway. The protein functions as a scaffolding adaptor protein in concert with TNF receptor associated factor 6 to mediate activation of NF kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in