Tau(Phospho Ser516/199) Polyclonal Antibody, 100ul Culture Media Mutations in TEAD1 cause Sveinsson's

Mutations in TEAD1 cause Sveinsson's chorioretinal atrophy

which requires the assistance of multiple molecular chaperones

Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma

and acts as a tumor suppressor in hepatoma cells

though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent

Tau(Phospho Ser516/199) Polyclonal Antibody, 100ul Culture Media Mutations in TEAD1 cause Sveinsson'sThis gene encodes the microtubule associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia,